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In which patients and how do I implement goiter prophylaxis?
● The drug of choice is potassium iodide.
● Primary prophylaxis is recommended for breast-feeding and for pregnant women beginning with week 12. It is especially critical in regions with iodine defficiency. Other at-risk groups are children during puberty, vegans, and vegetarians.
● Secondary prophylaxis is indicated after goiter-reduction therapy, but only in the absence of autonomous nodules. Start with a fraction of the target potassium iodide dosage and increase stepwise to account for the possibility of a disseminated (non-nodular) autonomy. Patients treated with thyreidoectomy or with radioiodine therapy may remain hypothyreotic despite potassium iodide supplementation, in which case they additionally require thryoxine substitution.
● Primary prophylaxis is recommended for breast-feeding and for pregnant women beginning with week 12. It is especially critical in regions with iodine defficiency. Other at-risk groups are children during puberty, vegans, and vegetarians.
● Secondary prophylaxis is indicated after goiter-reduction therapy, but only in the absence of autonomous nodules. Start with a fraction of the target potassium iodide dosage and increase stepwise to account for the possibility of a disseminated (non-nodular) autonomy. Patients treated with thyreidoectomy or with radioiodine therapy may remain hypothyreotic despite potassium iodide supplementation, in which case they additionally require thryoxine substitution.
Karteninfo:
Autor: LWojnowski
Oberthema: Medicine
Thema: Pharmacology
Schule / Uni: University Clinical Center
Ort: Mainz
Veröffentlicht: 24.05.2013