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Transgenic mouse models are essential tools in biomedical research, providing critical insights into gene function and disease mechanisms. By introducing specific genetic alterations, researchers can mimic human diseases, including cancer, cardiovascular diseases, and neurodegenerative disorders, within these models. These mice enable the study of complex biological processes in vivo, offering a deeper understanding of how particular genes contribute to health and disease. Transgenic mouse models also play a crucial role in evaluating the safety and efficacy of new drugs and therapeutic approaches before human clinical trials. Their use has accelerated the development of personalized medicine by allowing for the investigation of gene-environment interactions and the identification of potential drug targets, ultimately leading to more effective treatments for various conditions.