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26
Differential for ENDOgenous CS
ACTH Dependent:
2/3 are Cushings: 8:1 female/male. Gradual onset. 20-40 yo. Adenoma small / occult
1/6 Ectopic ACTH/CRH: 1:3 female/male. Oat cell carcinoma. Neuroendocrine tumors that might have somatostatin receptors
ACTH-Independent
1/6 are Adrenal (ACTH Independent): NO ANDROGEN EXCESS. Autoimmune / ectopic receptor / benign or malignant growth
2/3 are Cushings: 8:1 female/male. Gradual onset. 20-40 yo. Adenoma small / occult
1/6 Ectopic ACTH/CRH: 1:3 female/male. Oat cell carcinoma. Neuroendocrine tumors that might have somatostatin receptors
ACTH-Independent
1/6 are Adrenal (ACTH Independent): NO ANDROGEN EXCESS. Autoimmune / ectopic receptor / benign or malignant growth
