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18
Which drugs do I prescribe to a survivor of a myocardial infarction?
● Treatment is similar to that of patients with stable coronary artery disease and no history of myocardial infarction. The most important difference is that patients treated for myocardial infarction with percutaneous intervention receive an ADP receptor antagonist for up to 12 months.
● The drug of choice for acute pain relief is the short-acting nitrate glyceryl trinitrate.
● Prognostically, the most important are aspirin and statin treatments. Aspirin in LOW DOSE (75-100 mg/d), because higher dosing is not only more toxic (gastro-intestinal bleedings!), but also less effective as the resulting endothelial COX2 inhibition causes vasoconstriction. Statins are given irrespective of the initial lipid profile (fixed-dose approach).
● Beta blockers and angiotensin converting enzyme inhibitors are recommended and prescribed to most patients, but they are obligatory only in patients with additional problems, e.g. congestive heart failure.
● The drug of choice for acute pain relief is the short-acting nitrate glyceryl trinitrate.
● Prognostically, the most important are aspirin and statin treatments. Aspirin in LOW DOSE (75-100 mg/d), because higher dosing is not only more toxic (gastro-intestinal bleedings!), but also less effective as the resulting endothelial COX2 inhibition causes vasoconstriction. Statins are given irrespective of the initial lipid profile (fixed-dose approach).
● Beta blockers and angiotensin converting enzyme inhibitors are recommended and prescribed to most patients, but they are obligatory only in patients with additional problems, e.g. congestive heart failure.
Flashcard info:
Author: LWojnowski
Main topic: Medicine
Topic: Pharmacology
School / Univ.: University Clinical Center
City: Mainz
Published: 24.05.2013